| SKU-Pack Size | Availability | Size | Price | |
| EAB13831-30UL | In Stock | 30ul | $133.50 | |
| EAB13831-100UL | In Stock | 100ul | $298.50 | |
| EAB13831-200UL | In Stock | 200ul | $508.50 |
| Please select the country you are in to find your local distributor. |
| EbioCell | Phone:(540) 808-3925 | |
| Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
| Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
| Product Information | |
| Applications | WB, IHC-P |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:1000-5000 IHC-P=1:100-500 |
| MW (kDa) | 24 |
| Conjugate | Unconjugate |
| Specificity | SOCS1 Mouse Monoclonal Antibody detects endogenous levels of SOCS1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
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| Product Bioinformatics | |
| Synonym(s) | SOCS1 suppressor of cytokine signaling 1; JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; TIP-3; AISIMD; SOCS-1; SOCS1 |
| Gene Aliases | SOCS1 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SOCS1 also known as JAB, SSI1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Rat spleen cells, using SOCS1 Mouse Monoclonal Antibody (EAB13831) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
![]() Immunohistochemistry of paraffin-embedded Human spleen tissue, using SOCS1 Mouse Monoclonal Antibody (EAB13831) at 1:200 dilution.
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| Specific Protocols | |