Polyclonal Antibodies - AMBRA1 Rabbit Polyclonal Antibody

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AMBRA1 Rabbit Polyclonal Antibody

Catalog #：EAB11996

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11996-30UL	In Stock	30ul	$133.50
EAB11996-100UL	In Stock	100ul	$298.50
EAB11996-200UL	In Stock	200ul	$508.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	143
Conjugate	Unconjugate
Specificity	AMBRA1 Rabbit Polyclonal Antibody detects endogenous levels of AMBRA1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Autophagy and beclin 1 regulator 1; DCAF3; WDR94; AMBRA1
Gene Aliases	AMBRA1
UniProt ID	Q9C0C7
Entrez Gene ID	55626

Product Description

AMBRA1 also known as WDR94, KIAA1736 is a 1298 amino acid protein that contains three WD repeats. Enables enzyme binding activity and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including macroautophagy; positive regulation of free ubiquitin chain polymerization; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in cytosol. Part of Cul4-RING E3 ubiquitin ligase complex. Is active in cytoskeleton; mitochondrion; and nucleus. Biomarker of multiple system atrophy.

Product Image Gallery
Western blot analysis of extracts on 293T, NIH/3T3 cells, using AMBRA1 Rabbit Polyclonal Antibody (EAB11996) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol