Q9H816

SNM1B also known as DCLRE1B, APOLLO is a 532 amino acid nuclear protein that localizes to discrete foci and is likely required for DNA interstrand cross-link repair. SNM1B assists in the maintenance of telomeres during S-phase and interacts with TRF2 (telomeric repeat binding factor 2), a protein involved in telomeric organization and protection, in the early DNA-damage response. A member of the DNA repair metallo-beta-lactamase (DRMBL) family, SNM1B becomes phosphorylated following translation, either by ATM or ATR, and is encoded by a gene located on human chromosome 1.