Polyclonal Antibodies - KL/Klotho Rabbit Polyclonal Antibody

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KL/Klotho Rabbit Polyclonal Antibody

Catalog #：EAB22438

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22438-100UL	In Stock	100ul	$298.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300　 IF/ICC=1:50-300
MW (kDa)	116
Conjugate	Unconjugate
Specificity	KL/Klotho Rabbit Polyclonal Antibody detects endogenous levels of KL/Klotho protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Klotho; KLA; HFTC3; KL
Gene Aliases	KL
UniProt ID	Q9UEF7
Entrez Gene ID	9365

Product Description

Klotho also known as KL, HFTC3 is a type-I membrane protein that is related to beta-glucosidases. The amino terminal extracellular domain has two internal repeats, known as KL-1 and KL-2, which have partial sequence homology to beta-glucosidases and lactase glycosylceramidase, suggesting a role for Klotho in sphingolipid metabolism. The human klotho gene maps to chromosome 13q12 and encodes a 1012 amino acid protein that is abundant in the kidney and brain. Chronic renal failure (CRF) patients express lower levels of klotho mRNA and protein in the kidneys.

Product Image Gallery

Western blot analysis of extracts on DU145, Mouse kidney, Mouse brain cells, using Phospho-Mnk1 (Thr255) Rabbit Polyclonal Antibody (EAB22438) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Predicted band size: 116 kDa; Observed band size: 65,120 kDa

Immunohistochemistry of paraffin-embedded Human lung cancer tissue, using Phospho-Mnk1 (Thr255) Rabbit Polyclonal Antibody (EAB22438) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol