| SKU-Pack Size | Availability | Size | Price | |
| EAB22727-100UL | In Stock | 100ul | ¥2590.00 |
| Please select the country you are in to find your local distributor. |
| 北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
| 2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
| China | Beijing China | Website: www.mrkbio.com |
| Product Information | |
| Product | HuR/ELAVL1 Mouse Monoclonal Antibody |
| Applications | WB, IHC-P, IF/ICC |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse IgG2a |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:5000-20000 IHC-P=1:200-1000 IF/ICC=1:200-1000 |
| MW (kDa) | 36 |
| Conjugate | Unconjugate |
| Specificity | HuR/ELAVL1 Mouse Monoclonal Antibody detects endogenous levels of HuR/ELAVL1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
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| Product Bioinformatics | |
| Synonym(s) | ELAV like RNA binding protein 1; HUR; Hua; MelG; ELAV1; ELAVL1 |
| Gene Aliases | ELAVL1 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HuR also known as ELAVL1 is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. plays a crucial role in post-transcriptional regulation of gene expression by binding to AU-rich elements in the 3′-untranslated region of target mRNAs. This interaction stabilizes mRNA transcripts that would otherwise be rapidly degraded, thereby influencing the expression levels of genes involved in critical cellular processes such as growth, differentiation, and response to stress. HuR protein is ubiquitously expressed and is often overexpressed in various tumors, highlighting importance in cancer biology. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Hela, Jurkat, HEK293, MCF7, NIH/3T3 cells, using HuR/ELAVL1 Mouse Monoclonal Antibody (EAB22727) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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| Specific Protocols | |