SKU-Pack Size | Availability | Size | Price | |
EAB22406-100UL | In Stock | 100ul | ¥2290.00 |
Please select the country you are in to find your local distributor. |
北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IP, IF/ICC |
Species Reactivity | Human |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 IP=1:10-100 IF/ICC=1:50-200 |
MW (kDa) | 119 |
Conjugate | Unconjugate |
Specificity | Eg5 Rabbit Monoclonal Antibody detects endogenous levels of Eg5 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Kinesin family member 11; EG5; HKSP; KNSL1; MCLMR; TRIP5; KIF11 |
Gene Aliases | KIF11 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Eg5 also known as TRIP5, KIF11 is a slow plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of Eg5 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. Eg5 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). Eg5 is also known to be a member of the thyroid receptor interacting protein (Trip) family, and interacts with the thyroid hormone receptor only in the presence of thyroid. |
Product Image Gallery | |
Western blot analysis of extracts on Raji, 293T cells, using Eg5 Rabbit Monoclonal Antibody (EAB22406) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Immunocytochemistry analysis of Hela cell, using Eg5 Rabbit Monoclonal Antibody (EAB22406) at 1:100 dilution.
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Specific Protocols | |