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DSS (CAS: 68528-80-3)
Catalog #:EBC51167
  SKU-Pack Size Availability Size Price
EBC51167-100MG In Stock 100mg ¥390.00
EBC51167-500MG In Stock 500mg ¥590.00
EBC51167-1G In Stock 1g ¥790.00
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Product Information
Synonym(s) DSS; Disuccinimidyl octanedioate; DSS Crosslinker
Chemical Name Suberic acid bis(N-hydroxysuccinimide ester)
Application DSS is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
CAS Number 68528-80-3
Purity ≥99.0%
Molecular Weight 368.34
Molecular Formula C16H20N2O8
SMILES C1CC(=O)N(C1=O)OC(=O)CCCCCCC(=O)ON2C(=O)CCC2=O
Target & IC50 Non-cleavable Linker
Solubility DMSO: 250mg/mL (678.72 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.7149 ml 13.5744 ml 27.1488 ml
5 mM 0.5430 ml 2.7149 ml 5.4298 ml
10 mM 0.2715 ml 1.3574 ml 2.7149 ml
50 mM 0.0543 ml 0.2715 ml 0.5430 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

DSS is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm. 

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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