Other Biochemicals - DSS (CAS: 68528-80-3)

DSS (CAS: 68528-80-3)

Catalog #：EBC51167

DSS (CAS: 68528-80-3)

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Product Information

Synonym(s)

DSS; Disuccinimidyl octanedioate; DSS Crosslinker

Chemical Name

Suberic acid bis(N-hydroxysuccinimide ester)

Application

DSS is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

CAS Number

68528-80-3

Purity

≥99.0%

Molecular Weight

368.34

Molecular Formula

C16H20N2O8

SMILES

C1CC(=O)N(C1=O)OC(=O)CCCCCCC(=O)ON2C(=O)CCC2=O

Target & IC50

Non-cleavable Linker

Solubility

DMSO: 250mg/mL (678.72 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
DSS is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol