SKU-Pack Size | Availability | Size | Price | |
EAB22745-100UL | In Stock | 100ul | €297.70 |
Please select the country you are in to find your local distributor. |
Cambiotech | Phone£º+44 (0) 188 448801 | |
Lanwades Business Park, | E-mail£ºinfo@cambiotech.com | |
Ireland | Kobenhavn K, Ireland | Web£ºwww.cambiotech.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG2b |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF/ICC=1:50-300 |
MW (kDa) | 53 |
Conjugate | Unconjugate |
Specificity | ETEA/UBXD8 Mouse Monoclonal Antibody detects endogenous levels of ETEA/UBXD8 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Fas associated factor family member 2; ETEA; UBXD8; UBXN3B; FAF2 |
Gene Aliases | FAF2 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
ETEA also designated FAF2, UBX domain-containing protein 8 (UBXD8) is a 445-amino acid protein associated with atopic dermatitis (AD), a chronic noncontagious relapsing inflammatory skin disease characterized by eczematous skin lesions and also referred to as eczematous dermatitis. Other atopic diseases such as hay fever, asthma and conjunctivitis often occur along with AD. ETEA shows higher expression in T cells and eosinophils of patients with AD than in T cells and eosinophils of unaffected individuals. T cells are influential in the regulation of the inflammatory process of this disease. The persistence of AD is attributed to dysregulated apoptosis in T cells, eosinophils, and keratinocytes. ETEA may be involved in the resistance to apoptosis in T cells and eosinophils of AD patients. |
Product Image Gallery | |
Western blot analysis of extracts on 293, HepG2, Mouse lung cells, using ETEA/UBXD8 Mouse Monoclonal Antibody (EAB22745) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue, using ETEA/UBXD8 Mouse Monoclonal Antibody (EAB22745) at 1:100 dilution.
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Specific Protocols | |