SKU-Pack Size | Availability | Size | Price | |
EAB21147-100UL | In Stock | 100ul | €297.70 |
Please select the country you are in to find your local distributor. |
Cambiotech | Phone£º+44 (0) 188 448801 | |
Lanwades Business Park, | E-mail£ºinfo@cambiotech.com | |
Ireland | Kobenhavn K, Ireland | Web£ºwww.cambiotech.com |
Product Information | |
Applications | WB, ELISA |
Species Reactivity | Human |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 38 |
Conjugate | Unconjugate |
Specificity | CD86 Mouse Monoclonal Antibody detects endogenous levels of CD86 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | CD86 molecule; B70; B7-2; B7.2; LAB72; CD28LG2; CD86 |
Gene Aliases | CD86 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
CD86 also known as B7-2£¬B70 is a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
Product Image Gallery | |
Western blot analysis of extracts on HepG2, Molt4 cells, using CD86 Mouse Monoclonal Antibody (EAB21147) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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Specific Protocols | |