SKU-Pack Size | Availability | Size | Price | |
EAB21149-100UL | In Stock | 100ul | €297.70 |
Please select the country you are in to find your local distributor. |
Betaclonal | Phone£º+34 (0)91 471 6763 | |
29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
Product Information | |
Applications | WB, IHC-P, FC, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:100-500¡¡ FC=1:50-200 |
MW (kDa) | 93 |
Conjugate | Unconjugate |
Specificity | Caldesmon Mouse Monoclonal Antibody detects endogenous levels of Caldesmon protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Caldesmon 1; CDM; HCAD; LCAD; h-CD; H-CAD; L-CAD; NAG22; CALD1 |
Gene Aliases | CALD1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Caldesmon also designated CALD1, CDM is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
Product Image Gallery | |
Western blot analysis of extracts on Hela, NIH/3T3 cells, using Caldesmon Mouse Monoclonal Antibody (EAB21149) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue, using Caldesmon Mouse Monoclonal Antibody (EAB21149) at 1:200 dilution.
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Specific Protocols | |