Protein Agonists, Antagonists and Activators - Gastrin I (human) (CAS: 10047-33-3)

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Gastrin I (human) (CAS: 10047-33-3)

Catalog #：EBC51197

Datasheet

Gastrin I, human
(CAS: 10047-33-3)

SKU-Pack Size	Availability	Size	Price
EBC51197-1MG	In Stock	1mg	€232.70
EBC51197-5MG	In Stock	5mg	€778.70

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Product Information

Chemical Name

(3S,4Z,6S,7Z,9S,10Z,13Z,15S,16Z,18S,19Z,21S,22Z,24S,25Z,27S,28Z,30S,31Z,33S)-9-((1H-indol-3-yl)methyl)-21,24,27,30-tetrakis(2-carboxyethyl)-5,8,11,14,17,20,23,26,29,32-decahydroxy-3-((Z)-hydroxy(((S)-1-hydroxy-1-imino-3-phenylpropan-2-yl)imino)methyl)-33-

Application

Gastrin-1, human is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor.

CAS Number

10047-33-3

Purity

≥99.0%

Molecular Weight

2098.22

Molecular Formula

C97H124N20O31S

SMILES

CC(C[C@@](/N=C(O)/[C@](/N=C(O)/[C@]1([H])CCCN1C(C/N=C(O)/[C@]2([H])CCC(O)=N2)=O)([H])CC3=CNC4=CC=CC=C34)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/C/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@

Target & IC50

CCKBR

Solubility

DMSO: 50 mg/mL (23.83 mM)
NH4OH: 50 mg/mL (23.83 mM)

Preparing Stock Solutions

ConcentrationSolventMass	1 mg	5 mg	10 mg
1 mM	0.4766 ml	2.3830 ml	4.7660 ml
5 mM	0.0953 ml	0.4766 ml	0.9532 ml
10 mM	0.0477 ml	0.2383 ml	0.4766 ml
50 mM	0.0095 ml	0.0477 ml	0.0953 ml

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description

Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells. Gastrin I stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively). Gastrin I is also used in the culture of stomach, intestine and pancreas organoids.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol