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Aven Rabbit Polyclonal Antibody
Catalog #£ºEAB11456
  SKU-Pack Size Availability Size Price
EAB11456-30UL In Stock 30ul €115.70
EAB11456-100UL In Stock 100ul €258.70
EAB11456-200UL In Stock 200ul €440.70
If you want to get a larger packsize, Please contact your local distributor or
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Product Information
Applications WB, IHC-P, IF/ICC, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000¡¡
IHC-P=1:50-300¡¡
IF/ICC=1:50-300
MW (kDa) 39
Conjugate Unconjugate
Specificity Aven Rabbit Polyclonal Antibody detects endogenous levels of Aven protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Apoptosis and caspase activation inhibitor; PDCD12; AVEN
Gene Aliases AVEN
UniProt ID

Q9NQS1

Entrez Gene ID

57099

Product Description

Aven, a cell death regulator, is an important signal inducer in acute leuke-mias. Aven is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1′s ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. Aven is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of Aven in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), Aven expression may be a useful tool in prognosis prediction.

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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