Recombinant Antibodies - GCLM Rabbit Monoclonal antibody

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GCLM Rabbit Monoclonal antibody

Catalog #：EAB22498

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22498-100UL	In Stock	100ul	￡251.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:50-200 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	31
Conjugate	Unconjugate
Specificity	GCLM Rabbit Monoclonal antibody detects endogenous levels of GCLM protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Glutamate-cysteine ligase modifier subunit; γ-GCSm; GCSm-γ; GLCLR; GCLM
Gene Aliases	GCLM
UniProt ID	P48507
Entrez Gene ID	2730

Product Description

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Image Gallery

Western blot analysis of extracts on different cells, using GCLM Rabbit Monoclonal antibody (EAB22498) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: MCF7
Lane2: Hela
Lane3: NIH/3T3

Immunohistochemical analysis of paraffin-embedded Mouse liver tissue, using GCLM Rabbit Monoclonal antibody (EAB22498) at 1:200 dilution.

Immunohistochemical analysis of paraffin-embedded Human liver tissue, using GCLM Rabbit Monoclonal antibody (EAB22498) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol