SKU-Pack Size | Availability | Size | Price | |
EAB11377-30UL | In Stock | 30ul | £119.90 | |
EAB11377-100UL | In Stock | 100ul | £251.90 | |
EAB11377-200UL | In Stock | 200ul | £405.90 |
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CUlabSciences | Phone:+44 (0) 1232 330008 |
Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
Product Information | |
Applications | WB, IHC-P |
Species Reactivity | Human, Mouse |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 |
MW (kDa) | 93 |
Conjugate | Unconjugate |
Specificity | Acetyl-PCAF (Lys428) Rabbit Polyclonal Antibody detects endogenous levels of PCAF protein only when acetylated at Lys428. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Lysine acetyltransferase 2B; CAF; PCAF; P/CAF; KAT2B |
Gene Aliases | KAT2B |
UniProt ID | |
Entrez Gene ID |
Product Description | |
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. |
Product Image Gallery | |
![]() Western blot analysis of extracts on HepG2 cells, using Acetyl-PCAF (Lys428) Rabbit Polyclonal Antibody (EAB11377) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
![]() Immunohistochemical analysis of paraffin-embedded Human cervical carcinoma tissue, using Acetyl-PCAF (Lys428) Rabbit Polyclonal Antibody (EAB11377) at 1:200 dilution.
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Specific Protocols | |