SKU-Pack Size | Availability | Size | Price | |
EAB11369-30UL | In Stock | 30ul | €141.70 | |
EAB11369-100UL | In Stock | 100ul | €297.70 | |
EAB11369-200UL | In Stock | 200ul | €479.70 |
Please select the country you are in to find your local distributor. |
Betaclonal | Phone£º+34 (0)91 471 6763 | |
29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
Product Information | |
Applications | WB |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 |
MW (kDa) | 21 |
Conjugate | Unconjugate |
Specificity | Phospho-TIFA (Thr9) Rabbit Rabbit Polyclonal Antibody detects endogenous levels of TIFA protein only when phosphorylated at Thr9. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | TRAF interacting protein with forkhead associated domain; T2BP; T6BP; TIFAA; TIFA |
Gene Aliases | TIFA |
UniProt ID | |
Entrez Gene ID |
Product Description | |
TIFA encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. |
Product Image Gallery | |
Western blot analysis of extracts on Hela cells treated with LPS, using Phospho-TIFA (Thr9) Rabbit Rabbit Polyclonal Antibody (EAB11369) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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Specific Protocols | |