SKU-Pack Size | Availability | Size | Price | |
EAB22492-100UL | In Stock | 100ul | $298.50 |
Please select the country you are in to find your local distributor. |
EbioCell | Phone:(540) 808-3925 | |
Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
Product Information | |
Applications | WB, FC, ELISA |
Species Reactivity | Human, Rat |
Host / Isotype | Mouse IgG2b |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 FC=1:50-200 |
MW (kDa) | 19 |
Conjugate | Unconjugate |
Specificity | TNFRSF13C/BAFF-R Mouse Monoclonal Antibody detects endogenous levels of TNFRSF13C/BAFF-R protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | TNF receptor superfamily member 13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin; TNFRSF13C |
Gene Aliases | TNFRSF13C |
UniProt ID | |
Entrez Gene ID |
Product Description | |
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
Product Image Gallery | |
Western blot analysis of extracts on C6 cells, using TNFRSF13C/BAFF-R Mouse Monoclonal Antibody (EAB22492) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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Specific Protocols | |