SKU-Pack Size | Availability | Size | Price | |
EAB21169-100UL | In Stock | 100ul | €297.70 |
Please select the country you are in to find your local distributor. |
Betaclonal | Phone£º+34 (0)91 471 6763 | |
29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
Product Information | |
Applications | WB, IP, IF/ICC |
Species Reactivity | Human |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000¡¡ IP=1:50-200¡¡ IF/ICC=1:50-300 |
MW (kDa) | 218 |
Conjugate | Unconjugate |
Specificity | CHD4 Mouse Monoclonal Antibody detects endogenous levels of CHD4 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Chromodomain helicase DNA binding protein 4; CHD-4; Mi-2b; SIHIWES; Mi2-BETA; CHD4 |
Gene Aliases | CHD4 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
CHD4 also known as Mi-2b, Mi2-BETA belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using CHD4 Mouse Monoclonal Antibody (EAB21169) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Hela Lane2: U2OS Predicted band size: 218 kDa; Observed band size: 260 kDa |
Specific Protocols | |