| SKU-Pack Size | Availability | Size | Price | |
| EAB21168-100UL | In Stock | 100ul | $343.50 |
| Please select the country you are in to find your local distributor. |
| EbioCell | Phone:(540) 808-3925 | |
| Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
| Canada | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
| Product Information | |
| Applications | WB, IF/ICC |
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Applications Dilutions | WB=1:1000-5000 IF/ICC=1:100-500 |
| MW (kDa) | 218 |
| Conjugate | Unconjugate |
| Specificity | CHD4 Rabbit Monoclonal Antibody detects endogenous levels of CHD4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
| Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
|
| Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
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| Product Bioinformatics | |
| Synonym(s) | Chromodomain helicase DNA binding protein 4; CHD-4; Mi-2b; SIHIWES; Mi2-BETA; CHD4 |
| Gene Aliases | CHD4 |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CHD4 also known as Mi-2b, Mi2-BETA belongs to the SNF2/RAD54 helicase family. CHD4 plays a significant role in gene expression regulation by mediating histone deacetylation. CHD4′s ability to recruit histone deacetylases, such as HDAC1 and HDAC2, is vital for maintaining the balance between gene activation and repression, making CHD4 essential for proper cellular function and development. Dysregulation of CHD4 and associated complexes can lead to various diseases, including cancer, highlighting the importance of studying CHD4 in understanding transcriptional regulation and disease implications. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on NCCIT cells, using CHD4 Rabbit Monoclonal Antibody (EAB21168) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 218 kDa; Observed band size: 260 kDa |
| Specific Protocols | |