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Location：Home > Antibodies > Primary Antibodies > Monoclonal Antibodies
APPL1 Mouse Monoclonal antibody
Catalog #：EAB22717
Datasheet
  SKU-Pack Size Availability Size Price
EAB22717-100UL In Stock 100ul ￥2590.00
If you want to get a larger packsize, Please contact your local distributor or
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北京美瑞克生物科技有限公司 Phone：  +86 010-62890160 / 13691184142(微信同号)
2 / F, 128 malianwa North Road, Haidian District, E-mail：   mrkbio@163.com 
China Beijing China Website： www.mrkbio.com
Product Information
Applications WB, IHC-P, IF/ICC, FC
Species Reactivity Human, Mouse, Rat, Pig
Host / Isotype Mouse IgG2b
Clonality Monoclonal
Applications Dilutions WB=1:5000-20000　
IHC-P=1:100-500　
IF/ICC=1:100-500　
FC=1:100-500
MW (kDa) 80
Conjugate Unconjugate
Specificity APPL1 Mouse Monoclonal Antibody detects endogenous levels of APPL1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr-Horse All-All Species Expected
Product Bioinformatics
Synonym(s) Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1; APPL; MODY14; DIP13alpha; DIP13α; APPL1
Gene Aliases APPL1
UniProt ID

Q9UKG1
Entrez Gene ID

26060
Product Description

APPL1 also designated APPL, DIP13α has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.  
Product Image Gallery
Western blot analysis of extracts on different cells, using APPL1 Mouse Monoclonal Antibody (EAB22717) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Hela
Lane2: Jurkat
Lane3: HepG2
Lane4: HEK293
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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