P25490

YY1 also known as NF-E1, Delta, UCRBP is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. YY1 plays a crucial role in regulating diverse target genes, making YY1 essential for various biological processes. YY1 is located in the nucleus, where YY1 interacts with DNA to modulate gene expression. Four C-terminal zinc finger motifs and unique structural features at N-terminal enhance YY1′s versatility as a transcriptional regulator. Dual functionality as both an activator and repressor of transcription highlights YY1′s importance in maintaining cellular homeostasis and responding to developmental cues.