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APLP2 Rabbit Polyclonal Antibody
Catalog #:EAB11306
  SKU-Pack Size Availability Size Price
EAB11306-30UL In Stock 30ul £97.90
EAB11306-100UL In Stock 100ul £218.90
EAB11306-200UL In Stock 200ul £372.90
If you want to get a larger packsize, Please contact your local distributor or
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CUlabSciences Phone:+44 (0) 1232 330008
Cambridge House St Thomas' Place Ely, E-mail:sales@culabsciences.co.uk
United Kingdom Cambridge CB27 9RD UK Web:www.culabsciences.co.uk
Product Information
Applications WB, IHC-P, IF, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300
MW (kDa) 87
Conjugate Unconjugate
Specificity APLP2 Rabbit Polyclonal Antibody detects endogenous levels of APLP2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Amyloid beta precursor like protein 2; APPH; APPL2; CDEBP; APLP-2; APLP2
Gene Aliases APLP2
UniProt ID

Q06481

Entrez Gene ID

334

Product Description

APLP2 is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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