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¦Á-Actinin Rabbit Monoclonal Antibody
Catalog #£ºEAB22698
  SKU-Pack Size Availability Size Price
EAB22698-100UL In Stock 100ul €297.70
If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com
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SBT BioChem Srl Phone£º+39 05 7156 8147
Via Ponte di Bagnolo, 811 Bologna, E-mail£ºinfo@sbtbiochem.it
Italy Italy Web£ºwww.sbtbiochem.it
Product Information
Applications WB, IHC-P, IF/ICC
Species Reactivity Human, Mouse
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:1000-5000¡¡
IHC-P=1:50-200¡¡
IF/ICC=1:50-200
MW (kDa) 103
Conjugate Unconjugate
Specificity ¦Á-Actinin Rabbit Monoclonal Antibody detects endogenous levels of ¦Á-Actinin protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Actinin alpha 1; ¦Á Actinin; alpha Actinin; ACTN1
Gene Aliases ACTN1
UniProt ID

P12814

Entrez Gene ID

87

Product Description

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.  

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Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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