SKU-Pack Size | Availability | Size | Price | |
EAB22445-100UL | In Stock | 100ul | ¥2590.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IF/ICC, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:5000-20000 IF/ICC=1:100-500 |
MW (kDa) | 112 |
Conjugate | Unconjugate |
Specificity | Nesprin-3 Mouse Monoclonal antibody detects endogenous levels of Nesprin-3 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Spectrin repeat containing nuclear envelope family member 3; SYNE3; KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341 |
Gene Aliases | SYNE3 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Nesprin-3 also known as NESP3, SYNE3 belongs to the Nesprin family. Nesprin-3 is a protein that links intermediate filaments to the nucleus, regulates endothelial cell morphology, perinuclear cytoskeletal organization, and flow-induced cell polarization and migration. Involved in cytoskeleton organization; establishment of protein localization to membrane; and regulation of cell shape. Located in nuclear membrane. Part of meiotic nuclear membrane microtubule tethering complex. Biomarker of Huntington's disease. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Nesprin-3 Mouse Monoclonal antibody (EAB22445) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Hela Lane2: Jurkat Lane3: HEK293 Lane4: HepG2 |
Specific Protocols | |