Monoclonal Antibodies - Malic Enzyme 2/ME2 Mouse Monoclonal antibody

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Malic Enzyme 2/ME2 Mouse Monoclonal antibody

Catalog #：EAB22553

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22553-100UL	In Stock	100ul	$343.50

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email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500
MW (kDa)	65
Conjugate	Unconjugate
Specificity	Malic Enzyme 2/ME2 Mouse Monoclonal Antibody detects endogenous levels of Malic Enzyme 2/ME2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Malic enzyme 2; ODS1; ME2
Gene Aliases	ME2
UniProt ID	P23368
Entrez Gene ID	4200

Product Description

Malic enzyme 2(ME2) is a mitochondrial NAD-dependent malic enzyme. Found as a homotetramer, the main function of ME2 is to catalyze the anaplerotic reaction yielding pyruvate from (s)-malate. One single-nucleotide polymorphism of the ME2 gene has been associated with a phenotype manifested as psychosis. ME2 directly interacts with the malate shuttle system and has roles in neuronal synthesis of glutamate and gamma-amino butyric acid. This system has been shown to be altered in schizophrenia and bipolar disorder, which is also characterized by forms of epilepsy brought on by the role ME2 on ion channels in the brain.

Product Image Gallery
Western blot analysis of extracts on HL60, NIH/3T3, Jurkat cells, using Malic Enzyme 2/ME2 Mouse Monoclonal Antibody (EAB22553) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol