P05783

Cytokeratin 18 also known as CK-18, Keratin 18, KRT18 is a vital component of the cytoskeleton in epithelial cells, Cytokeratin 18 playing a crucial role in maintaining cell integrity and providing mechanical support. Cytokeratin 18 is primarily located in the cytoplasm of epithelial cells, where proper localization is essential for cellular architecture and function. Disruption of Cytokeratin 18 localization can lead to compromised cell stability and has been implicated in various pathological conditions, including cancer. Cytokeratin 18 serves as a significant marker for adenocarcinomas and basal cell carcinomas, making Cytokeratin 18 an important target for cancer diagnostics and research.