Monoclonal Antibodies - WWOX Mouse Monoclonal Antibody

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WWOX Mouse Monoclonal Antibody

Catalog #：EAB22689

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22689-100UL	In Stock	100ul	￡284.90

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse, Rat, Pig
Host / Isotype	Mouse IgG2a
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:200-1000
MW (kDa)	47
Conjugate	Unconjugate
Specificity	WWOX Mouse Monoclonal Antibody detects endogenous levels of WWOX protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	WW domain containing oxidoreductase; FOR; WOX1; DEE28; EIEE28; FRA16D; SCAR12; HHCMA56; PRO0128; SDR41C1; D16S432E
Gene Aliases	WWOX
UniProt ID	Q9NZC7
Entrez Gene ID	51741

Product Description

WWOX (WW domain containing oxidoreductase) protein is a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Product Image Gallery
Western blot analysis of extracts on different cells, using WWOX Mouse Monoclonal Antibody (EAB22689) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Lane1: MCF7 Lane2: HepG2 Lane3: Rat liver Predicted band size: 47 kDa; Observed band size: 40 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol