SKU-Pack Size | Availability | Size | Price | |
EAB22679-100UL | In Stock | 100ul | €336.70 |
Please select the country you are in to find your local distributor. |
SBT BioChem Srl | Phone£º+39 05 7156 8147 | |
Via Ponte di Bagnolo, 811 Bologna, | E-mail£ºinfo@sbtbiochem.it | |
Italy | Italy | Web£ºwww.sbtbiochem.it |
Product Information | |
Applications | WB, IHC-P, IF/ICC, FC |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:5000-20000¡¡ IHC-P=1:500-2000¡¡ IF/ICC=1:100-500¡¡ FC=1:100-500 |
MW (kDa) | 96 |
Conjugate | Unconjugate |
Specificity | Axin1 Mouse Monoclonal Antibody detects endogenous levels of Axin1 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Axin-1; AXIN; CMDOH; PPP1R49 |
Gene Aliases | AXIN1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Axin1 Mouse Monoclonal Antibody (EAB22679) at 1:5000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: K562 Lane2: A431 Lane3: HepG2 Lane4: Jurkat Predicted band size: 96 kDa; Observed band size: 110 kDa |
Specific Protocols | |