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Angiomotin Rabbit Polyclonal Antibody
Catalog #:EAB11418
  SKU-Pack Size Availability Size Price
EAB11418-30UL In Stock 30ul £97.90
EAB11418-100UL In Stock 100ul £218.90
EAB11418-200UL In Stock 200ul £372.90
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Product Information
Applications WB, ELISA
Species Reactivity Human, Mouse
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000
MW (kDa) 118
Conjugate Unconjugate
Specificity Angiomotin Rabbit Polyclonal Antibody detects endogenous levels of Angiomotin protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Angiomotin; AMOT; KIAA1071
Gene Aliases AMOT
UniProt ID

Q4VCS5

Entrez Gene ID

154796

Product Description

Angiomotin, also known as AMOT, is a 1,084 amino acid protein that belongs to the motin family of angiostatin binding proteins. Members of the motin family contain conserved coiled-coil domains and PDZ binding motifs at their C-termini. Expressed in skeletal muscle and placenta, Angiomotin localizes to the cell surface at tight junctions and is believed to be involved in tight junction maintenance. Angiomotin binds to angiostatin and plays a vital role in angiogenesis, promoting tubule formation and growth factor-induced migration of endothelial cells. This suggests that Angiomotin may be an important player in tumor angiogenesis and could serve as a potential therapeutic target in cancer. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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