USA£º(540) 808-3925
China£º400-117-0038
Spain
Shopping Cart
Sign in \ Register
Cytokeratin 14 Mouse Monoclonal Antibody
Catalog #£ºEAB22609
  SKU-Pack Size Availability Size Price
EAB22609-100UL In Stock 100ul €297.70
If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com
Please select the country you are in to find your local distributor.
Betaclonal Phone£º+34 (0)91 471 6763
29/1 Lomonosovsky Pr, E-mail£ºtech@betaclonal.com
Spain Madrid, Spain Web£ºwww.betaclonal.com
Product Information
Applications WB, IHC-P, IF/ICC, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Mouse IgG2b
Clonality Monoclonal
Applications Dilutions WB=1:500-2000¡¡
IHC-P=1:100-500¡¡
IF/ICC=1:100-500
MW (kDa) 53
Conjugate Unconjugate
Specificity Cytokeratin 14 Mouse Monoclonal Antibody detects endogenous levels of Cytokeratin 14 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) CK14; EBS3; EBS4; K14; NFJ; KRT14; Cytokeratin 14; CK-14; Cytokeratin14; Cytokeratin-14; Keratin-14; Keratin14; Koebner; EBS-3; EBS-4; K1C14
Gene Aliases KRT14
UniProt ID

P02533

Entrez Gene ID

3861

Product Description

Cytokeratin 14 (also designated KRT14 antibody, or Keratin 14 antibody) comprise a diverse group of intermediate filament proteins (IFPs) that are expressed in pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The a-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation and, in addition, they aid in the characterization of malignant tumors. In Bowen′s disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. The gene encoding human Cytokeratin 14 maps to chromosome 17q12-21. Mutations in this gene lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility.  

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Copyright 2015 EbioCell, Inc. All Rights Reserved. ¡¡±¸°¸ºÅ£º½òICP±¸2022005142ºÅ-1