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BRD7 Rabbit Polyclonal Antibody
Catalog #£ºEAB11134
  SKU-Pack Size Availability Size Price
EAB11134-30UL In Stock 30ul €115.70
EAB11134-100UL In Stock 100ul €258.70
EAB11134-200UL In Stock 200ul €440.70
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Product Information
Applications WB, ELISA
Species Reactivity Human, Mouse
Host / Isotype Rabbit IgG
Clonality Polyclonal
Applications Dilutions WB=1:500-2000
MW (kDa) 74
Conjugate Unconjugate
Specificity BRD7 Rabbit Polyclonal Antibody detects endogenous levels of BRD7 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Bromodomain containing 7; BP75; NAG4; CELTIX1; SMARCI1; BRD7
Gene Aliases BRD7
UniProt ID

Q9NPI1

Entrez Gene ID

29117

Product Description

BRD7 (bromodomain containing protein 7), also known as BP75 (75 kDa bromodomain protein), NAG4 or CELTIX1, is a 651 amino acid transcription regulation factor that contains one bromodomain and is expressed in liver, pancreas, intestines, kidney and cerebellum. Localizing to the nucleus, BRD7 plays an important role in cell cycle progression, signal-dependent gene expression and cell growth. BRD7 functions as a tumor suppressor, as is suggested by its apparent suppressive role on nasopharyngeal carcinoma (NPC) cell growth when overexpressed. Specifically, BRD7 negatively regulates the expression of cell cycle related proteins such as cyclin D1 and E2F-3, thereby inhibiting the G1-S progression. BRD7 also interacts with the centrosome associated protein BLOS2 and this BRD7-BLOS2 interaction inhibits the transcriptional suppression activity of BRD7 on various target genes. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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