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PRDM16 Mouse Monoclonal Antibody
Catalog #£ºEAB22443
  SKU-Pack Size Availability Size Price
EAB22443-100UL In Stock 100ul €297.70
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Betaclonal Phone£º+34 (0)91 471 6763
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Product Information
Applications WB, ELISA
Species Reactivity Human, Mouse
Host / Isotype Mouse IgG1
Clonality Monoclonal
Applications Dilutions WB=1:500-2000
MW (kDa) 140
Conjugate Unconjugate
Specificity PRDM16 Mouse Monoclonal Antibody detects endogenous levels of PRDM16 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) PR/SET domain 16; MEL1; KMT8F; LVNC8; PFM13; CMD1LL; PRDM16
Gene Aliases PRDM16
UniProt ID

Q9HAZ2

Entrez Gene ID

63976

Product Description

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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