Polyclonal Antibodies - PRDM16 Rabbit Polyclonal Antibody

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PRDM16 Rabbit Polyclonal Antibody

Catalog #：EAB11911

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB11911-30UL	In Stock	30ul	€115.70
EAB11911-100UL	In Stock	100ul	€258.70
EAB11911-200UL	In Stock	200ul	€440.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:50-300
MW (kDa)	140
Conjugate	Unconjugate
Specificity	PRDM16 Rabbit Polyclonal Antibody detects endogenous levels of PRDM16 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	PR/SET domain 16; MEL1; KMT8F; LVNC8; PFM13; CMD1LL; PRDM16
Gene Aliases	PRDM16
UniProt ID	Q9HAZ2
Entrez Gene ID	63976

Product Description

PRDM16 also known as MEL1, PFM13 is a crucial transcription factor localized in the nucleus, consisting of 1,276 amino acids that feature one SET domain and ten C2H2-type zinc fingers. This unique structure enables PRDM16 to interact with specific DNA sequences, thereby regulating gene expression essential for various cellular processes, including hematopoiesis and adipogenesis. PRDM16 plays a role in the pathogenesis of acute myeloid leukemia and myelodysplastic syndrome, where dysregulation can lead to malignancy. PRDM16 exists in three isoforms due to alternative splicing, which contributes to functional diversity and potential implications in cancer biology.

Product Image Gallery
Western blot analysis of extracts on K562 cells, using PRDM16 Rabbit Polyclonal Antibody (EAB11911) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol