SKU-Pack Size | Availability | Size | Price | |
EAB11101-30UL | In Stock | 30ul | $133.50 | |
EAB11101-100UL | In Stock | 100ul | $298.50 | |
EAB11101-200UL | In Stock | 200ul | $508.50 |
Please select the country you are in to find your local distributor. |
EbioCell | Phone:(540) 808-3925 | |
Imperial Business Park 4819 Emperor Boulevard, | E-mail:order@ebiocell.com | |
United States | Suite 408 Durham, NC 27703, USA | Web:www.ebiocell.com |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
MW (kDa) | 42 |
Conjugate | Unconjugate |
Specificity | Viperin Rabbit Polyclonal Antibody detects endogenous levels of Viperin protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Radical S-adenosyl methionine domain containing 2; SAND; cig5; vig1; cig33; RSAD2 |
Gene Aliases | RSAD2 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Viperin also known as RSAD2 (Radical S-adenosyl methionine domain-containing protein 2), CIG5 (Cytomegalovirus-induced gene 5 protein), vig1, CIG33, is a 361 amino acid protein that is involved in antiviral defense against pathogens such as Hep C, Cytomegalovirus and HIV-1. Localized to the cytosolic side of the endoplasmic reticulum and relocated to the Golgi apparatus upon viral infection, RSAD2 is thought to prevent viral budding by disrupting lipid rafts at the plasma membrane and supporting the Interferon-induced antiviral state of the cell. Additionally, RSAD2 can bind to and inactivate FDPS (an enzyme that is crucial for the synthesis of cholesterol and geranylated and farnesylated proteins), thereby playing a role in lipid synthesis. Overexpression of RSAD2 leads to abnormal lipid accumulation that is associated with atherosclerosis, a chronic inflammatory disease characterized by hardened arteries. |
Product Image Gallery | |
Western blot analysis of extracts on HepG2 cells, using Viperin Rabbit Polyclonal Antibody (EAB11101) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue, using Viperin Rabbit Polyclonal Antibody (EAB11101) at 1:100 dilution.
Immunohistochemical analysis of paraffin-embedded Human brain tissue, using Viperin Rabbit Polyclonal Antibody (EAB11101) at 1:100 dilution.
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Specific Protocols | |