Polyclonal Antibodies - Phospho-HPK1(Ser171) Rabbit Polyclonal Antibody

Location：Home > Antibodies > Primary Antibodies > Polyclonal Antibodies

Phospho-HPK1(Ser171) Rabbit Polyclonal Antibody

Catalog #：EAB22664

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22664-100UL	In Stock	100ul	$343.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB
Species Reactivity	Human, Mouse
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	91
Conjugate	Unconjugate
Specificity	Phospho-HPK1(Ser171) Rabbit Polyclonal Antibody detects endogenous levels of HPK1 protein only when phosphorylated at Ser171.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Mitogen-activated protein kinase kinase kinase kinase 1; Hematopoietic progenitor kinase 1; HPK1; MAP4K1
Gene Aliases	MAP4K1
UniProt ID	Q92918
Entrez Gene ID	11184

Product Description

HPK1 also known as MAP4K1 is a crucial serine/threonine kinase that plays a significant role in the regulation of the stress-responsive JNK/SAPK signaling pathway, which is vital for cellular responses to stress and inflammation. Located primarily in the cytoplasm, HPK1 interacts with various signaling molecules, including MEKK, to modulate the activity of downstream kinases, thereby influencing cellular processes such as apoptosis, differentiation, and proliferation. The proper functioning of HPK1 is essential for maintaining cellular homeostasis and responding to external stimuli, making HPK1 a key player in various physiological and pathological conditions. With an ability to activate the JNK signaling pathway, HPK1 is implicated in numerous diseases, including cancer and autoimmune disorders, highlighting the importance of studying HPK1 for therapeutic interventions.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol