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RACK1 Mouse Monoclonal antibody
Catalog #£ºEAB22657
  SKU-Pack Size Availability Size Price
EAB22657-100UL In Stock 100ul €336.70
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Product Information
Applications WB, IP, IHC-P, IF/ICC
Species Reactivity Human, Mouse, Rat, Pig
Host / Isotype Mouse IgG2a
Clonality Monoclonal
Applications Dilutions WB=1:5000-20000¡¡
IP=1:100-500
IHC-P=1:100-500¡¡
IF/ICC=1:100-500
MW (kDa) 35
Conjugate Unconjugate
Specificity RACK1 Mouse Monoclonal antibody detects endogenous levels of RACK1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) RACK1; Receptor for activated C kinase 1; H12.3; HLC-7; PIG21; GBLP; GNB2L1; Gnb2-rs1
Gene Aliases RACK1
UniProt ID

P63244

Entrez Gene ID

10399

Product Description

RACK1 (also designated HLC-7, GNB2L1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain. The RACK1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice and P.falciparum, and maps to human chromosome 5q35.3.  

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Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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