SKU-Pack Size | Availability | Size | Price | |
EAB22657-100UL | In Stock | 100ul | €336.70 |
Please select the country you are in to find your local distributor. |
Betaclonal | Phone£º+34 (0)91 471 6763 | |
29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
Product Information | |
Applications | WB, IP, IHC-P, IF/ICC |
Species Reactivity | Human, Mouse, Rat, Pig |
Host / Isotype | Mouse IgG2a |
Clonality | Monoclonal |
Applications Dilutions | WB=1:5000-20000¡¡ IP=1:100-500 IHC-P=1:100-500¡¡ IF/ICC=1:100-500 |
MW (kDa) | 35 |
Conjugate | Unconjugate |
Specificity | RACK1 Mouse Monoclonal antibody detects endogenous levels of RACK1 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | RACK1; Receptor for activated C kinase 1; H12.3; HLC-7; PIG21; GBLP; GNB2L1; Gnb2-rs1 |
Gene Aliases | RACK1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
RACK1 (also designated HLC-7, GNB2L1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain. The RACK1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice and P.falciparum, and maps to human chromosome 5q35.3. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using RACK1 Mouse Monoclonal antibody (EAB22657) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Hela Lane2: T47D Lane3: LO2 |
Specific Protocols | |