Monoclonal Antibodies - GRK2 Mouse Monoclonal Antibody

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GRK2 Mouse Monoclonal Antibody

Catalog #：EAB22605

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22605-100UL	In Stock	100ul	€297.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	SBT BioChem Srl	Phone：+39 05 7156 8147
	Via Ponte di Bagnolo, 811 Bologna,	E-mail：info@sbtbiochem.it
Italy	Italy	Web：www.sbtbiochem.it

Product Information
Applications	WB, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	80
Conjugate	Unconjugate
Specificity	GRK2 Mouse Monoclonal Antibody detects endogenous levels of GRK2 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	G protein-coupled receptor kinase 2; BARK1; ADRBK1; BETA-ARK1
Gene Aliases	GRK2
UniProt ID	P25098
Entrez Gene ID	156

Product Description

GRK2 (also designated BARK1, ADRBK1) is a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

Product Image Gallery

Western blot analysis of extracts on different cells, using GRK2 Mouse Monoclonal Antibody (EAB22605) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Jurkat
Lane2: Molt4
Lane3: Raji
Lane4: THP-1

Immunohistochemical analysis of paraffin-embedded Human endometrial cancer tissue, using GRK2 Mouse Monoclonal Antibody (EAB22605) at 1:200 dilution.

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue, using GRK2 Mouse Monoclonal Antibody (EAB22605) at 1:200 dilution.

Immunofluorescence analysis of NIH/3T3 cells, using GRK2 Mouse Monoclonal Antibody (EAB22605)(green) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol