SKU-Pack Size | Availability | Size | Price | |
EAB11145-30UL | In Stock | 30ul | ¥1090.00 | |
EAB11145-100UL | In Stock | 100ul | ¥2290.00 | |
EAB11145-200UL | In Stock | 200ul | ¥3690.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
MW (kDa) | 59 |
Conjugate | Unconjugate |
Specificity | Phospho-SPAK (Ser309) Rabbit Polyclonal Antibody detects endogenous levels of SPAK protein when phosphorylated at Ser309. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Serine threonine kinase 39; DCHT; PASK; SPAK |
Gene Aliases | STK39 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
SPAK, also known as STK39 (serine threonine kinase 39), DCHT or PASK, is a 547 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one protein kinase domain. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. |
Product Image Gallery | |
![]() Western blot analysis of extracts on COLO205 cells, using Phospho-SPAK (Ser309) Rabbit Polyclonal Antibody (EAB11145) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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Specific Protocols | |