Monoclonal Antibodies - CAB39 Mouse Monoclonal antibody

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CAB39 Mouse Monoclonal antibody

Catalog #：EAB22527

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22527-100UL	In Stock	100ul	$343.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000
MW (kDa)	40
Conjugate	Unconjugate
Specificity	CAB39 Mouse Monoclonal antibody detects endogenous levels of CAB39 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Calcium binding protein 39; MO25; CGI-66; CAB39
Gene Aliases	CAB39
UniProt ID	Q9Y376
Entrez Gene ID	51719

Product Description

CAB39(Calcium binding protein 39) also known as MO25, CGI-66 plays a crucial role in the regulation of the serine/threonine kinase LKB1, which is a key tumor suppressor involved in cellular energy homeostasis and metabolism. The interaction between CAB39 and LKB1 is vital for proper localization and activation of LKB1, as CAB39 facilitates LKB1 translocation from the nucleus to the cytoplasm, thereby enhancing tumor suppressor functions. Dysregulation of this complex can lead to impaired LKB1 activity, contributing to the development of Peutz-Jeghers Syndrome and increasing the risk of various cancers.

Product Image Gallery
Western blot analysis of extracts on K562, Mouse brain cells, using CAB39 Mouse Monoclonal antibody (EAB22527) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol