SKU-Pack Size | Availability | Size | Price | |
EAB22205-100UL | In Stock | 100ul | ¥2290.00 |
Please select the country you are in to find your local distributor. |
![]() |
北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC, FC, ELISA |
Species Reactivity | Human, Mouse |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 FC=1:50-200 |
MW (kDa) | 26 |
Conjugate | Unconjugate |
Specificity | Bcl-10 Mouse Monoclonal antibody detects endogenous levels of Bcl-10 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
|
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | BCL-10; BCL10; c-E10; C81403; CARMEN; cE10; CIPER; CLAP; IMD37; ME10 |
Gene Aliases | BCL10 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants |
Product Image Gallery | |
![]() Western blot analysis of extracts on different cells, using Bcl-10 Mouse Monoclonal antibody (EAB22205) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: NIH/3T3 Lane2: Hela Lane3: MCF7 Lane4: Jurkat ![]() Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue, using Bcl-10 Mouse Monoclonal antibody (EAB22205) at 1:200 dilution.
![]() Immunohistochemical analysis of paraffin-embedded Human liver tissue, using Bcl-10 Mouse Monoclonal antibody (EAB22205) at 1:200 dilution.
|
Specific Protocols | |