CCZ1 also known as CGI-43 is encoded by a gene located on human chromosome 7, a region associated with various genetic disorders, including osteogenesis imperfecta and Pendred syndrome, highlighting the importance of CCZ1 in both normal physiology and disease states. CCZ1 consists of 482 amino acids and is primarily localized to the lysosomal membrane, which is crucial for its role in cellular waste management and recycling processes. The lysosome is essential for degrading and recycling cellular components, and proper functioning of CCZ1 is vital for maintaining cellular homeostasis and preventing the accumulation of damaged organelles and proteins.