SKU-Pack Size | Availability | Size | Price | |
EAB11046-30UL | In Stock | 30ul | £97.90 | |
EAB11046-100UL | In Stock | 100ul | £218.90 | |
EAB11046-200UL | In Stock | 200ul | £372.90 |
Please select the country you are in to find your local distributor. |
CUlabSciences | Phone:+44 (0) 1232 330008 | |
Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
Product Information | |
Applications | WB, IHC-P, IF/ICC, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
MW (kDa) | 39 |
Conjugate | Unconjugate |
Specificity | Caseine Kinase 1 alpha Rabbit Polyclonal Antibody detects endogenous levels of Caseine Kinase 1 alpha protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Casein Kinase Iα; Casein Kinase 1α; CK1α; CKIα; CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p |
Gene Aliases | CSNK1A1 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Caseine Kinase 1 alpha , also known as CSNK1A1, CK1, is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1. Casein kinase Iα resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, Casein kinase Iα phosphorylates a large number of proteins. Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Caseine Kinase 1 alpha Rabbit Polyclonal Antibody (EAB11046) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: Hela Lane2: HT29 Predicted band size: 39 kDa; Observed band size: 35 kDa Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using Caseine Kinase 1 alpha Rabbit Polyclonal Antibody (EAB11046) at 1:100 dilution.
Immunofluorescence analysis of Hela cell, using Caseine Kinase 1 alpha Rabbit Polyclonal Antibody (EAB11046) at 1:100 dilution.
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Specific Protocols | |