SKU-Pack Size | Availability | Size | Price | |
EAB11041-30UL | In Stock | 30ul | £97.90 | |
EAB11041-100UL | In Stock | 100ul | £218.90 | |
EAB11041-200UL | In Stock | 200ul | £372.90 |
Please select the country you are in to find your local distributor. |
CUlabSciences | Phone:+44 (0) 1232 330008 | |
Cambridge House St Thomas' Place Ely, | E-mail:sales@culabsciences.co.uk | |
United Kingdom | Cambridge CB27 9RD UK | Web:www.culabsciences.co.uk |
Product Information | |
Applications | IHC-P, IF/ICC |
Species Reactivity | Human |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | IHC-P=1:100-500 IF/ICC=1:100-500 |
MW (kDa) | 58 |
Conjugate | Unconjugate |
Specificity | CD15/FUT4 Mouse Monoclonal Antibody detects endogenous levels of CD15/FUT4 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV |
Gene Aliases | FUT4 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
CD15, also known as Lewis X or LeX, is a carbohydrate antigen that is generated by FucT-IV (alpha 1,3-fucosyltransferase IV). Commonly found on the surface of leukocytes and some tumor cells, CD15 is a trisaccharide that is synthesized when FucT-IV transfers an α-fucose residue onto the β-GlcNAc moiety of cellular N-acetyllactosamines. CD15 functions as an adhesion molecule capable of calcium-mediated homotypic binding. Cells with high surface expression of CD15, therefore, exhibit strong self-aggregation (based on CD15-CD15 interaction) in the presence of calcium. Additionally, CD15 is thought to be a ligand for Selectins (proteins involved in mediating leukocyte-specific cellular interactions), further supporting its role as a cell-adhesion protein. |
Product Image Gallery | |
Immunohistochemical analysis of paraffin-embedded Human stomach tissue, using CD15/FUT4 Mouse Monoclonal Antibody (EAB11041) at 1:200 dilution.
Immunofluorescence analysis of Human liver cancer tissue, using CD15/FUT4 Mouse Monoclonal Antibody (EAB11041)(red) at 1:200 dilution.
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Specific Protocols | |