SKU-Pack Size | Availability | Size | Price | |
EAB22581-100UL | In Stock | 100ul | ¥2590.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC, FC |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse IgG2a |
Clonality | Monoclonal |
Applications Dilutions | WB=1:1000-5000 IHC-P=1:1000-5000 IF/ICC=1:50-300 FC=1:100-500 |
MW (kDa) | 110 |
Conjugate | Unconjugate |
Specificity | APN/CD13 Mouse Monoclonal antibody detects endogenous levels of APN/CD13 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | Aminopeptidase N; ANPEP; AP-M; AP-N; Apm; APN; CD13; GP150; KZP; Lap-1; LAP1; P150; PEPN; rAPN |
Gene Aliases | ANPEP |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. |
Product Image Gallery | |
![]() Western blot analysis of extracts on U937 cells, using APN/CD13 Mouse Monoclonal antibody (EAB22581) at 1:3000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 110 kDa; Observed band size: 150 kDa |
Specific Protocols | |