P08575

CD45 also known as LCA, GP180, B220, LY5, PTPRC is a member of the protein tyrosine phosphatase (PTP) family. CD45 is a transmembrane glycoprotein that is universally expressed on all nucleated hematopoietic cells, making it a critical marker for identifying and studying various immune cell populations. Located on the cell surface, CD45 plays an essential role in modulating signal transduction pathways by regulating tyrosine phosphorylation, which is pivotal for T and B cell receptor signaling and overall immune cell activation. This strategic cellular positioning allows CD45 to interact directly with key signaling molecules, thereby influencing immune responses and maintaining cellular communication within the immune system.