SKU-Pack Size | Availability | Size | Price | |
EAB11004-30UL | In Stock | 30ul | €115.70 | |
EAB11004-100UL | In Stock | 100ul | €258.70 | |
EAB11004-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
OlaSciences | Phone£º+33 (0) 9 77 4001 556 | |
87, rue des Suisses 65000 Nanterre, | E-mail£ºola@olasciences.com | |
France | France | Web£ºwww.olasciences.com |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF=1:50-300 |
MW (kDa) | 43 |
Conjugate | Unconjugate |
Specificity | Caspase-4 Rabbit Polyclonal Antibody detects endogenous levels of Caspase-4 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II; CASP4; Caspase-4 |
Gene Aliases | CASP4 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using Caspase-4 Rabbit Polyclonal Antibody (EAB11004) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: Hela Lane2: THP-1 Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue, using Caspase-4 Rabbit Polyclonal Antibody (EAB11004) at 1:100 dilution.
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Specific Protocols | |