SKU-Pack Size | Availability | Size | Price | |
EAB21198-100UL | In Stock | 100ul | ¥2290.00 |
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北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P, IF/ICC, FC |
Species Reactivity | Human, Mouse |
Host / Isotype | Rabbit IgG |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:50-200 FC=1:10-100 |
MW (kDa) | 57 |
Conjugate | Unconjugate |
Specificity | B7-H3/CD276 Rabbit Monoclonal Antibody detects endogenous levels of B7-H3/CD276 protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | CD276; B7-H3; B7RP-2; 4Ig-B7-H3 |
Gene Aliases | CD276 |
UniProt ID | |
Entrez Gene ID |
Product Description | |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Product Image Gallery | |
![]() Western blot analysis of extracts on Hela, 293T, MCF7 cells, using B7-H3/CD276 Rabbit Monoclonal Antibody (EAB21198) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 57 kDa; Observed band size: 90-110 kDa |
Specific Protocols | |