P09601

HO-1(HOxygenase 1) also known as HSP32, HMOX1 plays a crucial role in cellular defense mechanisms by catalyzing the degradation of heme into biliverdin, carbon monoxide, and free iron, thereby contributing to antioxidant protection and cellular homeostasis. The production of carbon monoxide by HO-1 is particularly significant as a signaling molecule in the brain, influencing neurotransmission and vascular regulation. This function is vital for maintaining normal physiological processes and protecting against oxidative stress, which can lead to various pathologies. HO-1 is highly inducible in response to stressors such as heavy metals and oxidative conditions, making HO-1 an important biomarker for studies related to inflammation and cellular stress responses.