SKU-Pack Size | Availability | Size | Price | |
EAB10368-30UL | In Stock | 30ul | €115.70 | |
EAB10368-100UL | In Stock | 100ul | €258.70 | |
EAB10368-200UL | In Stock | 200ul | €440.70 |
Please select the country you are in to find your local distributor. |
Betaclonal | Phone£º+34 (0)91 471 6763 | |
29/1 Lomonosovsky Pr, | E-mail£ºtech@betaclonal.com | |
Spain | Madrid, Spain | Web£ºwww.betaclonal.com |
Product Information | |
Applications | WB, IHC-P, IF, ELISA |
Species Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit IgG |
Clonality | Polyclonal |
Applications Dilutions | WB=1:500-2000¡¡ IHC-P=1:50-300¡¡ IF=1:50-300 |
MW (kDa) | 155 |
Conjugate | Unconjugate |
Specificity | IGFIR Rabbit Polyclonal Antibody detects endogenous levels of IGFIR protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
Product Bioinformatics | |
Synonym(s) | IGF 1 receptor; CD221; IGF-1R; IGF-IR; IGF1R; IGFR; CD221; IGFIR; JTK13; Insulin-like growth factor 1 receptor |
Gene Aliases | IGF1R |
UniProt ID | |
Entrez Gene ID |
Product Description | |
Insulin-like growth factor-I receptor (IGFIR) is an RTK that stimulates growth in many different cell types, blocks apoptosis, acts as an intermediate of many growth hormone responses and may stimulate the growth of some types of cancer. The IGF-IR cognate ligand insulin-like growth factor-I (IGF-I) promotes association of IGF-IR with Shc, GRB2 and Sos 1, which initiates Ras and ERK kinase cascades, thereby modifying transcription factor activity, such as activation of the Elk transcription factors. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using IGFIR Rabbit Polyclonal Antibody (EAB10368) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane1: HEK293 Lane2: NIH/3T3 Immunohistochemical analysis of paraffin-embedded Human testis tissue, using IGFIR Rabbit Polyclonal Antibody (EAB10368) at 1:200 dilution.
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Specific Protocols | |