Polyclonal Antibodies - CDCP1/CD318 Rabbit Polyclonal Antibody

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CDCP1/CD318 Rabbit Polyclonal Antibody

Catalog #：EAB14005

Datasheet

SKU-Pack Size	Availability	Size	Price
EAB14005-100UL	In Stock	100ul	￡251.90
EAB14005-200UL	In Stock	200ul	￡405.90

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	CUlabSciences	Phone：+44 (0) 1232 330008
	Cambridge House St Thomas' Place Ely,	E-mail：sales@culabsciences.co.uk
United Kingdom	Cambridge CB27 9RD UK	Web：www.culabsciences.co.uk

Product Information
Applications	WB, IHC-P
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Polyclonal
Applications Dilutions	WB=1:500-2000 IHC-P=1:50-300
MW (kDa)	93
Conjugate	Unconjugate
Specificity	CDCP1/CD318 Rabbit Polyclonal Antibody detects endogenous levels of CDCP1/CD318 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	CD318; CDCP1; RGD1305578; SIMA135; TRASK; UNQ2486/PRO5773; CDCP-1; SIMA-135;
Gene Aliases	CDCP1
UniProt ID	Q9H5V8
Entrez Gene ID	64866

Product Description

CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.

Product Image Gallery
Western blot analysis of extracts on PC3 cells, using CDCP1/CD318 Rabbit Polyclonal Antibody (EAB14005) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue, using CDCP1/CD318 Rabbit Polyclonal Antibody (EAB14005) at 1:50 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol